Michelle Kutzler
Associate Professor
OSU Campus
Department of Animal and Rangeland Sciences
561A Weniger Hall
Corvallis, OR 97331
United States
541-737-1401

Research

Basic canine reproductive physiology with specific emphasis on trophoblast invasion and modeling for pre-eclampsia.

Biography

Ph.D. Physiology, Cornell University, 2002

DACT, Diplomate, American College of Theriogenologists, 1999

DVM, Washington State University, 1993

B.S. Veterinary Science, Washington State University, 1990

Publications

Refereed Journal Articles

Kutzler MA, Tyson R, Grimes M, Timm K. Determination of testicular blood flow in camelids using vascular casting and color pulse-wave Doppler ultrasonography. Vet Med Internatl (in press).

Kutzler MA. Canine Neonatal Mortality. Clin Theriogenology (in press).

Luddy S, Kutzler MA. 2010. Contagious equine metritis within the United States: a review of the 2008 outbreak. J Equine Vet Science 30(8):393-400.

Kutzler MA. 2010. Current methods of twin reduction in the mare. Curr Res in Animal Science 2:15-32.

Daley JP, Kutzler MA, Bennet BW, Smith MC, Glaser AL, Appleton JA. 2010. Effector functions of camelid heavy-chain antibodies in immunity to West Nile virus. Clin Vaccine Immunol 17(2):239-246.

Kutzler MA. 2010. Effects of estrus induction on pregnancy rates in domestic bitches and queens. Clin Theriogenology 2(3):191-202.

Kutzler MA. 2010. Non-surgical alternatives for practitioners to control reproduction in dogs and cats. Clin Theriogenology 2(3):215-221.

Protain HJ, Kutzler MA, Valentine BA. 2009. Assessment of cytologic evaluation of preputial epithelial cells as a diagnostic test for detection of adrenocortical disease in castrated ferrets.  Am J Vet Res 70(5):619-623.

Kutzler MA, Lamb SV, Volkmann D. 2009. Comparison between vestibular and subcutaneous insertion of deslorelin implants for oestrus induction in bitches. Reprod Dom Anim 44(Suppl 2):1-4.

Gilbert RM, Bird KE, Kutzler MA. 2009. Determination of platelet aggregation responses in llamas. Vet Clin Pathol 38(1)42-45.

Plant JD, Kutzler MA, Cebra CK. 2007. Efficacy of topical eprinomectin in the treatment of Chorioptes sp. infestation in alpacas and llamas. Vet Dermatol 18(1):59-62.

Kutzler MA, Hofmaster IL.  2007. Aplasia of the tubular reproductive tract in a mare. J Am Vet Med Assoc 231(2):213-215.

Kutzler MA, Feleciano J, Valentine BA. 2007. Mandibular ameloblastoma in a mare. Equine Vet Educ 19(1).

Kutzler MA. 2007. Estrus induction and synchronization in canids and felids. Theriogenology 68(3):354-374.

Gilbert R, Kutzler M, Valentine BA, Semevolos S. 2006. Hyperandrogenism from an ovarian interstitial-cell tumor in an alpaca. J Vet Diagn Invest 18(6):605-607.

Kutzler MA, Shoemaker M, Valentine BA, Bildfell RJ, Tornquist SJ. 2006. Bilateral cystic rete testis in an alpaca (Lama pacos). J Vet Diagn Invest 18(3):303-306.

Kutzler M, Wood A. 2006.  Non-surgical methods of contraception and sterilization.  Theriogenology 66(3):514-525.

Volkmann DH, Kutzler MA, Wheeler R, Krekeler N, Klewitz J, Lamb SV.  2006.  Failure of hCG to support luteal function in bitches after estrus induction using deslorelin implants. Theriogenology 66(6-7):1502-1506.

Volkmann DH, Kutzler MA, Wheeler R, Krekeler N. 2006. The use of deslorelin implants for the synchronization of estrus in diestrous bitches. Theriogenology 66(6-7):1497-1501.

Kutzler MA. 2005. Induction and synchronization of estrus in dogs.  Theriogenology 64(3):766-775.

Kutzler MA. 2005. Semen collection in the dog.  Theriogenology 64(3):747-754.

Kutzler MA, Bildfell R, Gardner-Graff K, Delay J, Baker RJ, Mattson DE. 2004. West Nile virus in alpacas: a case report. J Am Vet Med Assoc 225(6):921-924.

Kutzler MA, Baker RJ, Mattson DE. 2004. Humoral immune response to West Nile virus vaccination in alpacas, llamas and horses. J Am Vet Med Assoc 225(3):414-416.

Fuller BC, Summer AD, Kutzler MA, Ruiz-Velasco V. 2004. A novel approach employing percutaneous intramyocardial injection using ultrasound imaging to label sympathetic neurons innervating rat cardiac muscle. Neurosci Lett 363(3):252-256.

Kutzler MA, Coksaygan T, Ferguson AD, Vincent SE, Nathanielsz PW. 2004. Maternally administered dexamethasone at 0.7 of gestation suppresses maternal and foetal pituitary and adrenal responses to hypoxaemia in sheep. Pediatr Res 55(5):755-763.

Kutzler MA, Coksaygan TC, Ferguson AD, Nathanielsz PW. 2004. Effects of maternally administered dexamethasone and acute hypoxemia at 0.7 gestation on blood pressure and placental perfusion in sheep. Hypertens Preg 23(1):75-90.

Kutzler MA, Ruane EK, Coksaygan T, Vincent SE, Nathanielsz PW. 2004. Effects of three courses of maternally administered dexamethasone at 0.7, 0.75 and 0.8 of gestation on prenatal and postnatal growth in sheep. Pediatrics 113(2):313-319.

Kutzler MA, Yeager AE, Mohammed HO, Meyers-Wallen VN. 2003. Accuracy of canine parturition date prediction using fetal measurement obtained by ultrasonography to estimate gestational age. Theriogenology 60(7):1309-1317.

Kutzler MA, Mohammed HO, Lamb SV, Meyers-Wallen VN.  2003. Accuracy of canine parturition date prediction using serum progesterone concentrations to estimate the preovulatory LH surge. Theriogenology 60(6):1187-1196.

Nathanielsz PW, Berghorn K, Derks JB, Giussani DA, Docherty C, Unno N, Davenport A, Kutzler M, Koenen S, Visser G, Nijland MJ. 2003. Life before birth: effects of cortisol on future cardiovascular and metabolic function. Acta Paediatr 92(7):766-772.

Kutzler MA, Molnar J, Schlafer DH, Nathanielsz PW. 2003. Maternal dexamethasone increases endothelin-1 sensitivity and endothelin a receptor expression in ovine fetal placental arteries.  Placenta 24:392-402.

Kutzler MA, Solter P, Hoffmann W, Volkmann DH. 2003. Identification and localization of alkaline phosphatase isoform in canine seminal plasma and gonadal tissues. Theriogenology 60:299-306.

Kutzler MA. 2001. Equine Turner's Syndrome (63, XO). J Am Vet Med Assoc  219(6):751-752.

Kutzler MA. 2001. Endometrial Cups. J Am Vet Med Assoc  218(2):205-206.

Books

Peterson M, Kutzler M (eds), Small Animal Pediatrics: The First 12 Months Of Life, Elsevier, St. Louis, 2010.Book Chapters:

Kutzler MA. Priapism. In: Cote E (ed), Clinical Veterinary Advisor (2nd ed), Elsevier-Mosby, Philadelphia (accepted December 2009).

Kutzler MA. Paraphimosis. In: Cote E (ed), Clinical Veterinary Advisor (2nd ed), Elsevier-Mosby, Philadelphia (accepted June 2009).

Kutzler MA. Prevention of breeding in the male. In: England G and von Heimendahl A (eds) BSAVA Manual of Reproduction and Neonatology (2nd ed), British Small Animal Veterinary Association, Gloucester, United Kingdom, 2010.

Kutzler MA. Pathophysiology of the Penis. In: Bojrab MJ, Monnet E (eds), Mechanisms of Disease in Small Animal Surgery (3rd ed), Teton NewMedia, Jackson WY, 2010.

Kutzler MA. Dystocia and obstetric crises. In: Silverstein D, Hopper K (eds) Small Animal Critical Care Medicine, Saunders, Philadelphia, 2009, 611-615.

Kutzler MA. Post-partum disorders of the bitch. In: Bonagura JD (ed), Kirk’s Current Veterinary Therapy XIV, Elsevier-Saunders, St. Louis, 2008, 999-1002.

Kutzler MA. Theriogenology section editor (35 chapters). In: Cote E (ed), Clinical Veterinary Advisor (1st ed), Elsevier-Mosby, Philadelphia, 2007.

Kutzler MA. Paraphimosis. In: Cote E (ed), Clinical Veterinary Advisor (1st ed), Elsevier-Mosby, Philadelphia, 2007, 809-810.

Mustaq MA, Kutzler MA. Parturition, Normal. In: Cote E (ed), Veterinary Clinical Advisor (1st ed), Elsevier-Mosby, Philadelphia. 2007, 815.

Kutzler MA. Considerations in Pregnant and Lactating Poisoned Patients. In: Peterson & Talcott (eds), Small Animal Toxicology (2nd ed), Saunders, 2006, 178-190.

Kutzler MA. Infertildad en la Hembra Canina (Canine female infertility). In: Wanke MM, Gobello K (eds), Reproduccion en caninos y felinos domesticos, Inter-Medica SA, Buenos Aires, Argentina, 2005.

Kutzler MA, Yeager AE. Canine Prostatic Diseases.  In: Ettinger SJ, Feldman EC (eds), Textbook of Veterinary Internal Medicine (6th ed), Elsevier-Saunders, St. Louis, 2005, 1809-1819.

Kutzler MA.  Pregnancy Termination and Contraception. In: Root Kustritz MV (ed), The Practical Veterinarian: Small Animal Theriogenology, Butterworth-Heinemann, St. Louis, 2003, 125-164.

Proceedings of National and International Conferences

Canine neonatal mortality. Annual Conference of the Society for Theriogenology; Seattle, WA, USA (September 1-3, 2010).

Effects of estrus induction on pregnancy rates in domestic bitches and queens. Annual Conference of the Society for Theriogenology; Seattle, WA, USA (September 1-3, 2010).

Non-surgical alternatives for practitioners to control reproduction in dogs and cats. Annual Conference of the Society for Theriogenology; Seattle, WA, USA (September 1-3, 2010).

Reproductive ultrasonographic imaging in the male Harbor seal. Annual Conference of the Society for Theriogenology; Seattle, WA, USA (September 1-3, 2010).

LH testing is accurate for diagnosing the presence of absence of testicular tissue in dogs. Annual Conference of the Society for Theriogenology; Seattle, WA, USA (September 1-3, 2010).

Whole blood selenium concentrations in pre-suckle newborn foals. Annual Conference of the Society for Theriogenology; Seattle, WA, USA (September 1-3, 2010).

Identifying gross chromosomal rearrangements that result in infertility in camelids. Annual Conference of the Society for Theriogenology; Albuquerque, NM, USA (August 25, 2009).

Testosterone decreases to basal values within 24 hours following castration in alpacas. Annual Conference of the Society for Theriogenology; Albuquerque, NM, USA (August 25, 2009).

Imipramine and xylazine treatment does not induce ejaculation in alpacas. Annual Conference of the Society for Theriogenology; Albuquerque, NM, USA (August 25, 2009).

Fascioliasis in llamas: treatment, mortality & difficulties in antemortem diagnosis. Annual International Camelid Health Conference; Corvallis, OR (March 14, 2009).

Semen evaluation and morphology. Annual Conference of the Society for Theriogenology; St. Louis, MO, USA (August 18, 2008).

Comparison between vestibular and subcutaneous insertion of deslorelin implants for oestrus induction in bitches. International Symposium on Canine and Feline Reproduction; Vienna, Austria (July 10, 2008).

Laser fulguration of endometrial cups to restore estrous cyclicity. World Equine Veterinary Association; Moscow, Russia (January 31, 2008).

Efficacy and dose response of passive administration of hyperimmunized West Nile virus serum in horses. World Equine Veterinary Association; Moscow, Russia (January 29, 2008).

Estrus induction and synchronization in canids and felids. Annual Conference of the Society for Theriogenology; Monterey, CA, USA (August 9, 2007).

Determination of testicular blood flow in llamas using vascular casting and Doppler color flow ultrasonography. Annual Conference of the Society for Theriogenology; Monterey, CA, USA (August 9, 2007).

Indications and methods for estrus induction in dogs. Annual Conference for the American Veterinary Medical Association; Washington, D.C. (July 14 – 18, 2007).

Canine semen collection and processing for shipment. Annual Conference for the American Veterinary Medical Association; Washington, D.C. (July 14 – 18, 2007).

Management of canine mammary neoplasia. Annual Conference for the American Veterinary Medical Association; Washington, D.C. (July 14 – 18, 2007).

Chromosomal aberrations as a cause for infertility in camelids. Annual International Camelid Health Conference; Corvallis, OR (March 8 – 11, 2007).

Identifying subfertility and infertility in male camelids. Annual International Camelid Health Conference; Corvallis, OR (March 8 – 11, 2007).

Diagnostic approach to infertility in female camelids. Annual International Camelid Health Conference; Corvallis, OR (March 8 – 11, 2007).

Administration of a single or multiple doses of injectable long-acting deslorelin (GnRH analogue) does not induce oestrus in bitches. Annual Meeting of the European Veterinary Society for Small Animal Reproduction; Budapest, Hungary (April 8, 2006).

A single injection of long-acting deslorelin does not induce estrus in bitches. Annual Conference of the Society for Theriogenology; St. Paul, MN, USA (August 22, 2006

Non-surgical methods of contraception and sterilization. Annual Conference of the Society for Theriogenology; St. Paul, MN, USA (August 22, 2006).

Assessment of fertility and infertility in male camelids. Annual Conference for the American Veterinary Medical Association; Honolulu, HI (July 18 – 22, 2006).

West Nile virus infection in camelids. Annual Conference for the American Veterinary Medical Association; Honolulu, HI (July 18 – 22, 2006).

Minute chromosome syndrome in alpacas. Annual Conference for the American Veterinary Medical Association; Honolulu, HI (July 18 – 22, 2006).

Semen collection in the dog. Annual Conference of the Society for Theriogenology; Charleston, SC, USA (August 12-13, 2005).

Preliminary studies on the use of imipramine and xylazine to induce ejaculation in llamas. Annual Conference of the Society for Theriogenology; Charleston, SC, USA (August 12-13, 2005).

Effect of X-radiation during transport on extended cooled canine sperm quality Annual Meeting of the European Veterinary Society for Small Animal Reproduction. Amsterdam, Netherlands (April 14, 2005).

Induction and synchronization of estrus in dogs. Annual Conference of the Society for Theriogenology; Charleston, SC, USA (August 12-13, 2005).

West Nile virus in alpacas and llamas. Annual International Camelid Health Conference; Corvallis, OR (March 3 – 4, 2005).

Breeding soundness evaluations in male camelids. Annual International Camelid Health Conference; Corvallis, OR (March 3 – 4, 2005).

Effect of undernutrition and re-alimentation on glucose metabolism in pregnant sheep. Annual Meeting for the Society of Gynecologic Investigation; Los Angeles, CA, USA (March 24, 2005).

Effect of undernutrition on glucose, insulin and leptin concentrations in pregnant sheep. Annual Meeting for the Society of Gynecologic Investigation; Los Angeles, CA, USA (March 24, 2005).

Immunolocalization of pancreatic leptin (ob) in pregnant sheep. Annual Meeting for the Society of Gynecologic Investigation; Los Angeles, CA, USA (March 24, 2005).

Effect of undernutrition on adipose leptin (ob) mRNA expression in pregnant sheep. Annual Meeting for the Society of Gynecologic Investigation; Los Angeles, CA, USA (March 24, 2005).

West Nile virus in camelids. Annual United States Animal Health Association Committee for Infectious Diseases of Cattle, Bison and Lamas; Greensboro, NC, USA (October 25, 2004).

Serum deslorelin levels in bitches after ovuplantÃ’ administration. Annual Meeting of the Society for Theriogenology (originally scheduled for presentation at 2001 meeting but meeting cancelled due to events of 9/11/01; presented September 18, 2003).

Identification and localization of alkaline phosphatase isoform in canine seminal plasma and gonadal tissues. Annual Meeting of the Society for Theriogenology (originally scheduled for presentation at 2001 meeting but meeting cancelled due to events of 9/11/01; presented September 18, 2003).

Maternal dexamethasone suppresses maternal and fetal ACTH and cortisol responses to hypoxemic stress in sheep. Annual Meeting for the Society of Gynecologic Investigation (March 30, 2003).

Maternal dexamethasone administration alters fetal blood pressure and adrenal blood flow responses to hypoxemic stress in sheep. Annual Meeting for the Society of Gynecologic Investigation (March 29, 2003).

Multiple weekly maternal dexamethasone ncreases placental endothelin B receptor density in sheep. Annual Meeting for the Society of Gynecologic Investigation (March 28, 2003).

Multiple weekly courses of dexamethasone to the pregnant ewe alter placentome morphology and increase placental glucocorticoid receptor protein expression. Annual Meeting for the Society of Gynecologic Investigation (March 28, 2003).

Deslorelin implant administration beneath the vulvar mucosa for the induction of synchronous estrus in bitches. Annual Meeting of the European Veterinary Society for Small Animal Reproduction; Liege, Belgium (May 11, 2002).

Effect of maternal hypoxemia on uterine blood flow and vascular resistance following 48-h dexamethasone exposure at 0.6 gestation in sheep. Annual Meeting for the International Society for the Study of Hypertension in Pregnancy; Toronto, Canada (June 5, 2002).

Comparison of vasoconstrictor responses to endothelin-1 in ovine maternal and fetal placental vessels following maternal administration of 3 weekly courses of dexamethasone or saline at 0.7, 0.75 and 0.8 gestation. Annual Meeting for the Society of Gynecologic Investigation; Los Angeles, CA, USA (March 21, 2002).

Multiple weekly maternal dexamethasone at doses that induce maximal fetal hypertension do not alter ovine fetal and newborn organ weight. Annual Meeting for the Society of Gynecologic Investigation; Los Angeles, CA, USA (March 21, 2002).

Multiple weekly maternal glucocorticoid treatment prolongs ovine gestation but does not lower birth weight or alter postnatal growth. Annual Meeting for the Society for Gynecologic Investigation; Toronto, Canada (March 15, 2001).

Influence of body weight and litter size on gestation length. Annual Meeting of the European Veterinary Society for Small Animal Reproduction; Milan, Italy (March 1, 2001).

Canine estrus induction using the GnRH agonist, deslorelin. Annual Meeting of the European Veterinary Society for Small Animal Reproduction; Milan, Italy (March 1, 2001).

Effect of litter size on the accuracy of predicting the whelping date using ultrasonography. International Congress on Animal Reproduction; Stockholm, Sweden (July 5, 2000).

Proceedings of Regional Conferences

Canine infertility. Marion Polk Veterinary Association Annual Continuing Education Conference; Woodburn, OR, USA (November 4, 2007).

Small animal reproductive pharmacology. Marion Polk Veterinary Association Annual Continuing Education Conference; Woodburn, OR, USA (November 4, 2007).

Canine reproductive emergencies. Marion Polk Veterinary Association Annual Continuing Education Conference; Woodburn, OR, USA (November 4, 2007).

Equine endometritis. Marion Polk Veterinary Association Annual Continuing Education Conference; Woodburn, OR, USA (November 4, 2007).

Camelid infertility. Marion Polk Veterinary Association Annual Continuing Education Conference; Woodburn, OR, USA (November 4, 2007).

Role of prolactin in mammary adenocarcinoma in dogs and cats. Annual Northwest Reproductive Sciences Symposium; Moscow, ID, USA (March 23, 2007).

Effect of endothelin-1 on coronary blood flow in the fetal sheep. 8thAnnual Northwest Reproductive Sciences Symposium; Portland, OR, USA (April 21, 2006).

Effect of undernutrition and re-alimentation on glucose metabolism in pregnant sheep. 7thAnnual Northwest Reproductive Sciences Symposium; Seattle, WA, USA (April 22, 2005).

Effect of undernutrition on glucose, insulin and leptin concentrations in pregnant sheep. Annual Northwest Reproductive Sciences Symposium; Seattle, WA, USA (April 22, 2005).

Immunolocalization of pancreatic leptin (ob) in pregnant sheep. Annual Northwest Reproductive Sciences Symposium; Seattle, WA, USA (April 22, 2005).

Effect of undernutrition on adipose leptin (ob) mRNA expression in pregnant sheep. Annual Northwest Reproductive Sciences Symposium; Seattle, WA, USA (April 22, 2005).

Influence of poor nutrition during pregnancy on maternal glucose metabolism in sheep. Annual Meeting of the Northwest Reproductive Sciences Symposium; Corvallis, OR, USA (April 2, 2004).

Maternal dexamethasone suppresses maternal and fetal ACTH and cortisol responses to hypoxemic stress in sheep. Annual Meeting of the Northwest Reproductive Sciences Symposium; Moscow, ID, USA (April 18, 2003).

Maternal dexamethasone administration alters fetal blood pressure and adrenal blood flow responses to hypoxemic stress in sheep. Annual Meeting of the Northwest Reproductive Sciences Symposium; Moscow, ID, USA (April 18, 2003).

Multiple weekly maternal dexamethasone ncreases placental endothelin B receptor density in sheep. Annual Meeting of the Northwest Reproductive Sciences Symposium; Moscow, ID, USA (April 18, 2003).

Multiple weekly courses of dexamethasone to the pregnant ewe alter placentome morphology and increase placental glucocorticoid receptor protein expression. Annual Meeting of the Northwest Reproductive Sciences Symposium; Moscow, ID, USA (April 18, 2003).

West Nile virus infection in camelids: diagnosis, treatment and prevention. Colorado Camelid Veterinarians; Denver, CO, USA Corvallis, OR (November 1, 2003).

Canine reproductive problems. Annual Conference for the Oregon Veterinary Medical Association; Corvallis, OR (March 22 – 23, 2003).

Feline reproductive management. Annual Conference for the Oregon Veterinary Medical Association; Corvallis, OR (March 22 – 23, 2003).

Canine semen freezing. Annual Conference for the Oregon Veterinary Medical Association; Corvallis, OR (March 22 – 23, 2003).

Comparison of vasoconstrictor responses to endothelin-1 in ovine maternal and fetal placental vessels following maternal administration of 3 weekly courses of dexamethasone or saline at 0.7, 0.75 and 0.8 gestation. Annual Meeting of the Northwest Reproductive Sciences Symposium; Moscow, ID, USA (April 26, 2002).

Multiple weekly maternal dexamethasone at doses that induce maximal fetal hypertension do not alter ovine fetal and newborn organ weight. Annual Meeting of the Northwest Reproductive Sciences Symposium; Moscow, ID, USA (April 26, 2002).

Companion animal reproductive pharmacology. Cornell University Annual Conference for Veterinarians; Ithaca, NY (March 23 – 25, 2001).

Clinical management of equine paraphimosis. Cornell University Annual Conference for Veterinarians; Ithaca, NY (March 23 – 25, 2001).

Canine semen freezing. Cornell University Annual Conference for Veterinarians; Ithaca, NY (March 23 – 25, 2001).

Feline reproductive management. Annual Fred Scott Feline Symposium; Ithaca, NY (July 30, 2000).

Feline early-age neutering. Annual Fred Scott Feline Symposium; Ithaca, NY (July 30, 2000).

Canine reproductive problems. Cornell University Annual Conference for Veterinarians; Ithaca, NY (March 24, 2000).

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