My goal is the discovery of key gene networks that affect sperm mobility phenotype. The discovery of sperm mobility and the analysis of this trait resulted in three outcomes that were wholly unexpected in the mid-1990s: (1) a patent followed by technology transfer, (2) a model explaining in vivo storage of sperm within the hen’s oviduct, which in turn resulted in (3) a new experimental approach for semen preservation based upon bioenergetic theory. Having explained sperm mobility in terms of sperm cell behavior, mitochondrial function, and proteome composition, it is my hope that SNP-based information will ultimately be used for improving semen quality within pedigree lines of poultry.
Ph.D. Animal Physiology, Clemson University, 1981
M.S. Poultry Science, Clemson University, 1978
B.S. Biology, Bob Jones University, 1976
Kirby JD, Froman DP. 2000. Reproduction in the male bird. In: Sturkie's Avian Physiology, 5th Edition, GC Whittow, editor. Academic Press, pp. 597-615.
Froman DP, Kirby JD. 2000. Reproduction in male poultry. In: Reproduction in Farm Animals, 7th Edition, ESE Hafez, editor. Williams & Wilkins, pp. 237-242.
Peer Reviewed Journal Articles
Invited Manuscript: Froman DP, Feltmann AJ. 2010. A new approach to sperm preservation based on bioenergetic theory. J Anim Sci 88:1314-1320.
Invited Manuscript: Froman DP, Feltmann AJ, Pendarvis K, Cooksey AM, Burgess SC, Rhoads DD. 2010. A proteome-based model for sperm mobility phenotype. J Anim Sci (in press).
Pizzari T, Worley K, Burke T, Froman DP. 2008. Sperm competition dynamics: ejaculate fertilizing efficiency changes differentially with time. BMC Evolutionary Biology 8:332-338.
Froman, DP, Wardell JC, Feltmann AJ. 2006. Sperm mobility: Deduction of a model explaining phenotypic variation in roosters (Gallus domesticus). Biol Reprod 74:487-491.
Froman DP. 2006. Application of the sperm mobility assay to primary broiler breeder stock. J Applied Poultry Research 15:280-286.
Froman DP, Kirby JD, Rhoads DD. 2006. An expressed sequence tag analysis of the chicken reproductive tract transcriptome. Poultry Sci 85:1438-1441.
Froman DP, Feltmann AJ. 2005. Fowl (Gallus domesticus) sperm motility depends upon mitochondrial calcium cycling driven by extracellular sodium. Biol Reprod 72:97-101
Froman DP, Kirby JD. 2005. Sperm mobility: Phenotype in roosters (Gallus domesticus) determined by mitochondrial function. Biol Reprod 72:562-567.
Okimoto R, Froman D, Pratchard L, Locovare H, Kirby J. 2003. The complete DNA sequence of a chicken mitochondrial genome associated with maternal type that exhibits high sperm mobility. GenBank Accession Number AY235570.
Okimoto R, Froman D, Pratchard L, Locovare H, Kirby J. 2003. The complete DNA sequence of a chicken mitochondrial genome associated with maternal type that exhibits low sperm mobility. GenBank Accession Number AY235571.
Froman DP, Bowling ER, Wilson JL. 2003. Sperm mobility phenotype not determined by sperm quality index. Poultry Sci 82:496-502.
Bowling ER, Froman DP, Davis AJ, Wilson JL. 2003. Attributes of broiler breeder males characterized by low and high sperm mobility. Poultry Sci 82:1796-1801.
Donoghue AM, Kirby JD, Froman DP, Lerner SP, Crouch AN, King LA, Donoghue DJ, Sonstegard TS. 2003. Field testing the influence of sperm competition based on sperm mobility in breeder turkey toms. Brit Poultry Sci 44:498-504.
Froman DP. 2003. Deduction of a model for sperm storage in the oviduct of the domestic fowl (Gallus domesticus). Biol Reprod 69:248-253.
Pizzari T, Froman DP, Birkhead TR. 2002. Pre- and post-insemination episodes of sexual selection in the fowl, Gallus g. domesticus. Heredity 88:112-116.
Froman DP, Pizzari T, Feltmann AJ, Castillo-Juarez H, Birkhead TR. 2002. Sperm mobility: Mechanisms of fertilizing efficiency, genetic variation and phenotypic relationship with male status in the domestic fowl, Gallus g. domesticus. Proc R Soc London B 269:607-612.
Froman DP, Feltmann AJ. 2000. Sperm mobility: Phenotype in roosters (Gallus domesticus) determined by concentration of motile sperm and straight line velocity. Biol Reprod 62:303-309
King LM, Kirby JD, Froman DP, Sonstegard TS, Harry DE, Darden JR, Donoghue AM. 2000. Efficacy of sperm mobility assessment in commercial flocks and the relationship of sperm mobility and insemination dose on fertility in turkeys. Poultry Sci 79:1797-1802.